Sugar Isomerases

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منابع مشابه

Development of Novel Sugar Isomerases by Optimization 1 of Active Sites in Phospho Sugar Isomerases for

6 Department of Bioscience and Biotechnology, Konkuk University, Seoul 143-701, 7 Republic of Korea 8 Journal section: Biotechnology 9 10 Running title: YEOM ET AL. 11 DEVELOPMENT OF NOVEL SUGAR ISOMERASE 12 13 14 15 *Corresponding author. Mailing address: Department of Bioscience and Biotechnology, 16 Konkuk University, 1 Hwayang-Dong, Gwangjin-Gu, Seoul 143-701, Republic of 17 Korea. Phone: 8...

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Prolyl isomerases in yeast.

Prolyl isomerases are enzymes that catalyze cis-trans isomerization of peptidyl-prolyl bonds and span three structurally unrelated protein families: the cyclophilins, FKBPs, and parvulins. The genome of the budding yeast Saccharomyces cerevisiae encodes eight different cyclophilins (Cpr1 to Cpr8), four FKBPs (Fpr1 to Fpr4), and a single parvulin (Ess1). Remarkably, two of these proteins, cyclop...

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Prolyl Isomerases and Nuclear Function

(calcium-signal modulating cyclophilin ligand), and Cyp40 is part of the Hsp90/Hsc70 complex that binds steroid receptors. Likewise, FKBP12 is a subunit of two calcium Tony Hunter Molecular Biology and Virology Laboratory The Salk Institute channels (the ryanodine receptor and the IP 3 receptor), 10010 North Torrey Pines Road is needed for the function of the MDR drug efflux pump La Jolla, Cali...

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Thiol isomerases in thrombus formation.

Protein disulfide isomerase (PDI), ERp5, and ERp57, among perhaps other thiol isomerases, are important for the initiation of thrombus formation. Using the laser injury thrombosis model in mice to induce in vivo arterial thrombus formation, it was shown that thrombus formation is associated with PDI secretion by platelets, that inhibition of PDI blocked platelet thrombus formation and fibrin ge...

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Prolyl Isomerases as New Therapeutic Targets

Prolyl isomerases comprise three main protein families totalling over thirty mammalian genes, and several hundred orthologues across the biological domains, with a very broad spectrum of physiological functions and disease implications. Potent small molecule inhibitors exist for members of the three main mammalian families (cyclophilins, FKBPs and parvulins),. but, until recently, these protein...

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ژورنال

عنوان ژورنال: Agricultural and Biological Chemistry

سال: 1963

ISSN: 1881-1280,0002-1369

DOI: 10.1271/bbb1961.27.271